The objectives of the Clinical Trials and Cohort Studies Grant scheme are: 

• To support high-quality clinical trials and cohort studies that address important gaps in knowledge, leading to relevant and implementable findings for the benefit of human health. This grant opportunity is open to research proposals for clinical trials and/or cohort studies of any size – that is, they may be large or small clinical trials or cohort studies.

• The Clinical Trials and Cohort Studies Grant scheme is not intended to provide ongoing support from NHMRC, and grant funding does not support infrastructure costs. Grantees will be required to report against milestones at twelve-month intervals.

The intended outcomes of the Clinical Trials and Cohort Studies Grants scheme are improvements in health and wellbeing, health care practice or policy, as a result of:

• High-quality clinical trials that provide reliable evidence of the effects of health-related interventions on health outcomes (or appropriate surrogates).

• High-quality cohort studies that provide reliable evidence on the relation of important risk factors and other exposures to health-related outcomes.

• High quality retrospective cohort studies that provide reliable evidence on the relation of important risk factors and other exposures to health-related outcomes.

The objective of the MRFF 2026 Clinician Researchers: Nurses, Midwives and Allied Health Grant Opportunity is to provide grants of financial assistance to support medical research and medical innovation projects that:

• Stream 1 (Targeted Call for Research): conduct clinician researcher-led research within health services to accelerate translation of evidence into practice.

• Stream 2 (Targeted Call for Research): conduct clinician researcher-led research that strengthens health system performance, workforce innovation and/or service improvement.

The intended outcome of the research funded by this grant opportunity is to improve the health and well-being of Australians by supporting nurses, midwives and allied health professionals to improve the quality of health care, practice and systems by undertaking applied research in health care that:

The objective of this grant opportunity is to provide grants of financial assistance to support medical research and medical innovation projects that: 

• Investigate and trial approaches, including adapting successful trials, to advance equity in primary health care services. 

• Are co-designed with primary health care services and consumers. 

The objective of this grant opportunity is to provide a grant of financial assistance to an organisation or consortium to run an Aboriginal and Torres Strait Islander Community-Controlled program to support Aboriginal and/or Torres Strait Islander led health and medical research projects.

This grant opportunity offers funding to support medical research and medical innovation programs of research that deliver a ‘moonshot’ by creating a treatment for a currently serious and incurable health condition, through a series of linked projects. The program of research can propose to develop novel health technologies and/or re?purpose existing health technologies in a novel way.

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The initial application process to secure funding through this grant opportunity will be conducted in two stages:

• expression of interest (EOI) – outlining a proposed program of research comprising of a series of linked projects with a 10-year time horizon

• full application, (invitation only – following EOI) for a project of up to 5 years under the program of research.

Applicants may propose to commence research at any stage in the research pipeline from proof-of-concept, with the intention of achieving full implementation of the proposed technology in 10 years.

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Funding for subsequent projects under the program of research that continue to progress the technology towards full implementation can be sought by submitting additional full applications to this grant opportunity (i.e. applicants do not need to recommence with an EOI). These applications may be submitted by invitation only.